Kif11 control

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August undefined, 2024

Web18 dec. 2024 · Kif11 immunostaining in the mouse retina showed localization in the retinal pigment epithelium, the inner segment, and the ciliary region of the photoreceptor layer, … Web4 jan. 2024 · Co-targeting KIF11 and BRD4 with ARRY-520 and JQ1 reduced MPNST cell viability, synergistically killing a much higher proportion of MPNST cells than control …

Entry - *148760 - KINESIN FAMILY MEMBER 11; KIF11

Web34 KIF11 Silencer Select Pre-designed, Validated, and Custom siRNA in Standard, HPLC, and In-vivo Ready Purities. Popular ... Related Controls; Assay ID 118429 View Assay on Map Other Species Targeted Gene. KIF11. Species Human Transcripts. 1 RefSeq (NM) ... Web23 mei 2016 · KIF11 gene mutations cause a rare autosomal dominant inheritable disease called microcephaly with or without chorioretinopathy, lymphedema, or mental retardation (MCLMR). Recently, such mutations... premier league players 2020

KIF11 Gene - GeneCards KIF11 Protein KIF11 Antibody

Web8 sep. 2024 · Genomic instability (GIN) has an important contribution to the pathology of colorectal cancer (CRC). Therefore, we selected mitosis and cytokinesis kinesins, KIF11 and KIF14, as factors of potential clinical and functional value in CRC, as their aberrant expression has been suspected to underlie GIN. We examined the expression and the … Web11 jan. 2024 · This study aimed to investigate the mechanisms underlying the development of the androgen-independent phenotype in prostate cancer. Methylation patterns were detected in androgen-independent and androgen-dependent lymph node carcinoma of the prostate (LNCaP) prostate carcinoma cells based on methylated DNA … WebSilencer® KIF11 (Eg5) siRNA (Human, Mouse, Rat) Store at or below –20°C. Do not store in a frost-free freezer. Catalog #: AM4639 Component: KIF11 (Eg5) siRNA Negative Control #1 siRNA Amount: 5 nmol 2 nmol Volume: 100 μL 40 μL Concentration: 50 μM 50 μM Target Information: Gene Symbol: KIF11 Full Gene Name: Kinesin family member 11 scotland v holland 1978 world cup

3832 - Gene ResultKIF11 kinesin family member 11

AM4639 Silencer KIF11 (Eg5) siRNA - Thermo Fisher Scientific

WebHowever, given that a total immunoreactive score allowed us to categorize most PDACs as KIF11-downregulated tumors, and these had an adverse prognosis, it is a functional role of KIF11 in controlling genome integrity [15,24] that would potentially explain some of the pro- and anti-tumorigenic effects of this protein depending on the context and ... WebAdenomatous polyposis coli (APC) also known as deleted in polyposis 2.5 (DP2.5) is a protein that in humans is encoded by the APC gene. The APC protein is a negative regulator that controls beta-catenin concentrations and interacts with E-cadherin, which are involved in cell adhesion.Mutations in the APC gene may result in colorectal cancer.. APC is … scotland v holland highlightsWeb18 dec. 2024 · After analysis of these and previously reported patients, the authors proposed 4 distinct types of KIF11-related retinal changes: type 1, with subclinical retinal changes that may include retinal thinning or decreased full-field electroretinographic (ERG) responses; type 2, showing retinal dystrophy with characteristic findings on optical … scotland v holland live

"Web11 apr. 2024 · Identification of exosomes and expression of miR-619-5p. A The morphology of cell exosomes was observed by the transmission electron microscope at 120 kv.B identification of exosomes by Western blot, CD63 as positive marker and Calnexin as negative marker.C and D Detection of miR-619-5P expression in GC cells and their … " - Kif11 control

Kif11 control

Inhibitors of KIF11 have been developed as chemotherapeutic agents in the treatment of cancer. Drugs that specifically inhibit only human Kinesin-5 are alternatives to the taxanes and vinc alkaloids that target microtubules, and thus all cells, and that are currently used clinically. Inhibition of Kinesin-5 causes cells to undergo mitotic arrest, undergo apoptosis and form monoaster spindles. The first KIF11 inhibitor, monastrol was discovered in a chemical screen of … WebKIF11 belongs to the kinesin family and encodes a spindle motor protein that contributes to the assembly of the bipolar spindle during mitosis. 24 Whether KIF11 regulates the …

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WebKIF11 protein expression summary - The Human Protein Atlas. KIF11. PROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA. KIF11 … WebQuality Control Testing: 12.5% SDS-PAGE Stained with Coomassie Blue. Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. ... KIF11; Gene Alias: EG5,HKSP,KNSL1,TRIP5; Gene Description: kinesin family member 11; Omim ID: 148760; Gene Ontology: Hyperlink;

WebIMP3 regulates CD44 and KIF11. (A) Total CD44 protein was measured in whole cell lysates 48 h after transfection. Treatment with IMP3 siRNA resulted in a significant decrease in CD44 protein... Web16 mei 2024 · KIF11 is an evolutionarily conserved microtubule motor protein that functions in centrosome and chromosome dynamics in mitosis. Interestingly, the yeast ortholog of …

WebAmbion™ Silencer ™ KIF11 (Eg5) Positive Control siRNA (Human, Mouse, Rat) is ideal for developing and optimizing siRNA experiments. 5 nmol is provided, along with an … WebOur data provide extensive evidence to demonstrate that KIF11 inhibitors showed pronounced antitumor activity, acting in key points of tumorigenesis and cancer …

WebStructural retinal changes of KIF11-associated retinopathy in comparison to those in a healthy control on OCT images. The photoreceptor layer is highlighted in yellow. Images in the right...

Web23 apr. 2024 · KIF11 belongs to the kinesin superfamily, is involved in spindle dynamics, and encodes a molecular motor protein known as Eg5, which is involved in chromosome … premier league player injuriesWebInhibiting KIF11 expression in lentivirus-suppressed cells revealed that KIF11 inhibition significantly reduced cell viability and colony formation, inhibited migration and invasion, … premier league players 2021Web3 jul. 2024 · KIF11 knockdown remarkably suppressed thyroid cancer cell proliferation as well as induced cell apoptosis of thyroid cancer cells, suggesting that KIF11 may be a potential therapeutic target for thyroid cancer. 2. Materials and Methods 2.1. Antibodies, Primers, and Plasmids premier league player of theWeb19 sep. 2024 · Notably, the KIF11 mRNA expression elevated with the increasing histological grade of CCA from the TCGA database, suggesting KIF11 expression may … premier league players coming outWebKIF11, a plus end-directed kinesin, as a key gene in benzo(a)pyrene-induced non-small cell lung cancer. Five novel copy number variations detected in patients with familial … premier league player bettingWebUK-007170-20 Edit-R Kif11 crRNA Control Kit (Mouse) 20 nmol 168,00 € CRISPRControls2024 142,80 € 23 € Ambient UK-007070-20 Edit-R KIF11 crRNA Control Kit (Human) 20 nmol 168,00 € CRISPRControls2024 142,80 € 23 € Ambient U-006000-01-05 Edit-R Lethal crRNA Control #1 5 nmol 110,50 € CRISPRControls2024 93,93 € 23 € … scotland v holland footballWeb17 okt. 2006 · Description. An autosomal dominant disorder that involves an overlapping but variable spectrum of central nervous system and ocular developmental anomalies. … premier league players currently injured